20 Prayers for Depression (+ Bible Verses)

Whether you’re religious, spiritual, or not quite sure where you stand, sometimes we all need a little extra help to get through the dark times.

That’s why we’ve put together a collection of prayers and Bible verses to provide comfort, hope, and perspective when you or someone you care about is going through a tough time.

Now, I know not everyone believes in the power of prayer or finds solace in religious texts, and that’s totally okay. This isn’t a one-size-fits-all kind of deal. But for those who do find strength in spirituality, these prayers and verses might offer a bit of light in a dark tunnel.

And hey, even if you’re not religious, sometimes just the act of reading comforting words can offer a momentary escape from what you’re going through. So, feel free to read on and take what serves you.

Remember: If you're struggling with depression, it's crucial to consult healthcare professionals for a comprehensive treatment plan. You don't have to go through it alone.

A Prayer for Acceptance

Dear God, help me accept that it’s okay to not be okay. Teach me to embrace my vulnerabilities and see them not as weaknesses, but as opportunities for Your grace to shine through. Let me find peace in knowing I’m a work in progress. Amen.

A Prayer for Self-Compassion

Heavenly Father, I’m so hard on myself, especially when I’m feeling down. Help me to show myself the same kindness and understanding that I’d offer to a friend in need. Remind me that I’m not alone and that it’s okay to ask for help. Amen.

A Prayer for Courage to Seek Help

Dear God, I know I can’t do this on my own. Give me the courage to reach out for help, whether it’s from friends, family, or professionals. Let me not be ashamed of my struggle but see it as an opportunity to grow stronger through Your grace. Amen.

A Prayer for Emotional Strength

Lord, my emotions feel like a rollercoaster that I can’t get off. Please grant me the emotional strength to cope with my depression. Help me to understand my feelings, and give me the wisdom to manage them in a way that honors You. Amen.

A Prayer for Clarity of Mind

Dear God, my thoughts are clouded by depression. Clear away the fog, and help me see things as they truly are. Give me the clarity to make wise decisions and the focus to engage with life in a meaningful way. Amen.

A Prayer for Breaking the Cycle

Lord, I feel trapped in a never-ending cycle of sadness and despair. Please give me the strength and wisdom to break free. Show me the steps I need to take, and help me to follow through, one day at a time. Amen.

A Prayer for Inner Peace

Heavenly Father, my mind is a storm of negative thoughts. Please bring calm and peace to my inner world. Let Your tranquility replace my anxiety and fear, and help me find rest in You. Amen.

A Prayer for Finding Light in the Darkness

Dear God, I feel lost and alone in this darkness that seems to consume me. Please be my guiding light, leading me out of this gloom. Help me see the beauty in life that I’ve forgotten, and give me the strength to take steps, however small, toward healing. Amen.

A Prayer for Reclaiming Joy

Dear God, I miss the joy that once filled my life. Help me find it again. Show me how to appreciate the small blessings each day brings and let those moments of happiness build up into a renewed sense of purpose and joy. Amen.

A Prayer for Gratitude

Dear God, it’s hard to feel grateful when I’m this low. Open my eyes to the blessings that I’ve overlooked. Let a grateful heart be the new lens through which I see my life and help me to focus on the positives. Amen.

A Prayer for Daily Resilience

Dear God, every day feels like a battle. Equip me with the armor I need to face each day’s challenges. Give me the resilience to get through the tough moments and the presence of mind to recognize the good ones. Amen.

A Prayer for Motivation

Heavenly Father, I lack the energy and motivation to do even simple tasks. Please infuse me with Your divine energy. Help me to take small steps toward recovery, celebrating each little victory along the way. Amen.

A Prayer for Patience in Healing

Lord, I want to be better now, but I know healing takes time. Grant me the patience to wait for the changes I’m working toward. Help me trust in Your timing and Your plan for my life. Amen.

A Prayer for Self-Worth

Dear God, my self-esteem is so low right now, and I feel unworthy of love, even Your love. Remind me that I am made in Your image and that I am deserving of love and kindness, both from others and myself. Amen.

A Prayer for Healing Relationships

Lord, depression has strained my relationships with the people I care about. Help me mend these bonds and open up about my struggles. Let love and understanding be the foundation upon which we rebuild. Amen.

A Prayer for Family and Friends

Lord, my depression doesn’t just affect me; it also affects those I love. Please give my family and friends the understanding and patience they need to support me. And help me to accept their love and care, even when I feel undeserving. Amen.

A Prayer for Letting Go of Guilt

Heavenly Father, I often blame myself for feeling this way, as if it’s my fault. Help me to let go of this guilt and understand that depression is an illness, not a character flaw. Guide me toward healing and self-forgiveness. Amen.

A Prayer for Freedom from Shame

Heavenly Father, I’m often ashamed of my depression, as if it’s a mark against me. Free me from this shame and help me understand that my worth is not determined by my mental health. Let me find my identity in You. Amen.

A Prayer for Spiritual Connection

Heavenly Father, in my depression, I sometimes feel distant from You. Draw me closer in this time of suffering. Let me feel Your love and grace, reminding me that even in my lowest moments, You are there. Amen.

A Prayer for Future Hope

Lord, right now, it’s hard to imagine a future without this pain. But I know that with Your help, better days are possible. Give me hope for a brighter future and the perseverance to work towards it. Amen.


Bible Verses to Help with Depression

Life can be incredibly tough sometimes. Whether you’re religious or not, the Bible has been a source of comfort for many people going through difficult times, including those struggling with depression.

So, let’s dive into some Bible verses that might offer you a bit of solace. I’ll be using the American Standard Version (ASV) for these references.

Psalm 34:17-18

"The righteous cry, and Jehovah heareth, And delivereth them out of all their troubles. Jehovah is nigh unto them that are of a broken heart, And saveth such as are of a contrite spirit."

This verse reminds us that you’re not alone, even when it feels like you are. It’s saying that God hears you and is close to those who are struggling.

Isaiah 41:10

"Fear thou not, for I am with thee; be not dismayed, for I am thy God; I will strengthen thee; yea, I will help thee; yea, I will uphold thee with the right hand of my righteousness."

When you’re feeling weak or scared, this verse offers a promise of strength and support. It’s like a spiritual pep talk, urging you not to give in to fear because you’re not facing it alone.

Matthew 11:28

"Come unto me, all ye that labor and are heavy laden, and I will give you rest."

If you’re worn out from the emotional toll of depression, this verse invites you to find rest and relief. It’s an open invitation, saying, “Hey, if you’re struggling, come find comfort here.”

2 Corinthians 1:3-4

"Blessed be the God and Father of our Lord Jesus Christ, the Father of mercies and God of all comfort; who comforteth us in all our affliction, that we may be able to comfort them that are in any affliction, through the comfort wherewith we ourselves are comforted of God."

This one’s a bit of a mouthful, but it’s basically saying that the comfort you receive in your times of struggle can become a source of comfort for others. It’s a reminder that your experiences, as tough as they are, can make you a beacon of hope for others going through similar hardships.

Philippians 4:13

"I can do all things in him that strengtheneth me."

When you’re at the end of your rope, this verse serves as a reminder that you have a source of strength beyond yourself. It’s like a spiritual energy boost, encouraging you to keep going.

Psalm 42:11

"Why art thou cast down, O my soul? And why art thou disquieted within me? Hope thou in God; for I shall yet praise him, Who is the help of my countenance, and my God."

This verse captures that inner dialogue many of us have when we’re feeling down. It’s like a pep talk to your soul, reminding you to find hope even when things look bleak.

Proverbs 3:5-6

"Trust in Jehovah with all thy heart, And lean not upon thine own understanding. In all thy ways acknowledge him, And he will direct thy paths."

When you’re depressed, making decisions or even just getting through the day can feel overwhelming. This verse encourages you to trust in something greater than yourself, suggesting that you don’t have to carry your burdens alone.

Romans 8:38-39

"For I am persuaded, that neither death, nor life, nor angels, nor principalities, nor things present, nor things to come, nor powers, nor height, nor depth, nor any other creature, shall be able to separate us from the love of God, which is in Christ Jesus our Lord."

Feeling unloved or unworthy is a common symptom of depression. This verse is a powerful reminder that nothing can separate you from divine love, even when you’re struggling to love yourself.

1 Peter 5:7

"Casting all your anxiety upon him, because he careth for you."

When you’re weighed down by worries and depression, this verse offers a way to lighten the load. It’s like saying, “Hey, you don’t have to carry this all by yourself. There’s someone who cares for you and wants to help.”

Psalm 143:7-8

"Answer me speedily, O Jehovah; My spirit faileth: Hide not thy face from me, Lest I become like them that go down into the pit. Cause me to hear thy lovingkindness in the morning; For in thee do I trust: Cause me to know the way wherein I should walk; For I lift up my soul unto thee."

This one speaks to the urgency we often feel when we’re depressed. It’s a plea for guidance and a reminder to trust in a higher power when our own strength seems to fail us.

Jeremiah 29:11

"For I know the thoughts that I think toward you, saith Jehovah, thoughts of peace, and not of evil, to give you a future and a hope."

When you’re struggling with depression, the future can seem bleak or even nonexistent. This verse offers a glimmer of hope, reminding you that there’s a plan for your well-being, even if you can’t see it right now.

Lamentations 3:22-23

"It is of Jehovah’s lovingkindnesses that we are not consumed, because his compassions fail not. They are new every morning; great is thy faithfulness."

This verse acknowledges that life is tough, but it also offers a daily renewal of hope. It’s like saying, “Each day is a new chance for things to get better.”

James 4:8

"Draw nigh to God, and he will draw nigh to you."

When you’re feeling isolated or distant, this verse offers a simple but powerful promise: Take one step toward a higher power, and you’ll be met halfway. It’s an invitation to engage, even when it’s the last thing you feel like doing.


So, there you have it—a collection of prayers and Bible verses that some people find comforting when they’re dealing with depression. Whether you read through every word or just skimmed, I hope you found something that resonated with you, even if it’s just a tiny bit.

The main takeaway here is that you’re not alone, even when it feels like you’re carrying the weight of the world on your shoulders.

Sometimes, a few words—whether they’re from an ancient text or just something a friend says—can offer a glimmer of hope or a moment of peace. And sometimes, that’s enough to get you through the next minute, hour, or day.

If you’re going through a tough time, please don’t hesitate to seek professional help. There’s no shame in asking for support, whether it’s from a therapist, a doctor, or a trusted friend. Take care, and remember, you’ve got this.

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Leah is a creative soul with a passion for telling stories that matter. She channels her natural curiosity and imagination into thought-provoking articles and inspiring content. She is also a registered nurse dedicated to helping others and making a positive impact.